Abstract: The Intergovernmental panel for Climate Change(IPCC)Report Series issued stronger and stronger conclusion that the climate change in the 20th century is very much likely the largest climate change in recent 1000 years and warming the 20th century is attributed to the green house gases increase. Recent studies suggest that the climate change is accelerated and the future climate change may well be larger than previously projected. However，there are opposite opinions as well both abroad and domestic.This article will discuss the issue of will the future climate change in China lager or smaller than projected. Our analyses will based on the climate model behavior in simulating the last glacial maximum and the mid­Holocene climates，as well as the recent changes in temperature，sea level，green house gases，mountain glaciers，and so on. All these information seems to lead to a conclusion that the future climate change in China might larger than projected by the state­of­the­art climate models.In order to better adjust to the climate change，recognizing the key vulnerable regions to climate change is essential. The paper suggests several key vulnerable regions，including the source region of the three major rivers(Yangtze River，Yellow River，and Lantsang River)，the Central North China，North East China，North West China，and South Eastern China. Key issues for the source region of the three rivers include the fast melting of the mountain glaciers in the Tibetan Plateau region and the associated water cycle and supply to source region of the river. In the north part of the country，precipitation change and the related water resource change are the key concerns，particular for the Central North China. In the South Eastern China，we should pay more attention to the variation of climate extreme，including the flood，typhoon landfalling，and heat waves.